Sagaia (USA)
Saint Sword (USA)
Saint Sword (Japan)
Same! Same! Same! (Japan)
Sampras Tennis 96 (Europe) (J-Cart)
Samurai Shodown (Europe)
Samurai Spirits (Japan)
Sangokushi II (Japan)
Sangokushi III (Japan)
Sangokushi Retsuden - Ransei no Eiyuutachi (Japan)
Sanguozhi Liezhuan - Luanshi Qunying (China)
Sanguozhi V (China) (Unl)
Saturday Night Slammasters (USA)
Saturday Night Slammasters (Europe)
Scooby Doo Mystery (USA)
Scrabble (Europe) (Proto)
SD Valis (Japan)
SeaQuest DSV (USA)
SeaQuest DSV (Europe)
Second Samurai (Europe)
Sega Sports 1 (Europe)
Sega Top Five (Brazil)
Senjou no Ookami II ~ Mercs (World)
Sensible Soccer (Europe) (En,Fr,De,It)
Sensible Soccer (Europe) (En,Fr,De,It) (Beta)
Sensible Soccer - International Edition (Europe) (En,Fr,De,It)
Sesame Street Counting Cafe (USA)
Shadow Blasters (USA)
Shadow of the Beast (USA, Europe)
Shadow of the Beast - Mashou no Okite (Japan)